Sabathia was struck in the right thigh by a John Mayberry comebacker in the second inning at Bright House Field, then picked up the ball and threw out the runner at first base.
Team medical staff and manager Joe Girardi immediately charged out of the dugout to look at Sabathia, but they only got as far as the foul line before Sabathia put up his hand and waved them back to their seats.
"It still hurts, but it's all right," said Sabathia, who iced the area after he exited. "I've got a lot of meat down there."
Rebounding from his annual bad second start of Spring Training, Sabathia limited Philadelphia to three hits over five scoreless innings, walking none and striking out two.
"CC looked really good," Girardi said. "He still didn't even hit his pitch count. That's pretty much the CC we're used to seeing."
Sabathia credited the work that he and pitching coach Larry Rothschild did in the bullpen.
"I have a pause in my delivery," Sabathia said. "I was kind of floating and drifting through it instead of just staying there, gathering it and going. I was conscious of it in the bullpen today, and it translated into the game."