The Yankees got out to an early lead on a solo home run by Robinson Cano off Pavano in the first inning, but the Twins came right back with a solo shot by Michael Cuddyer in the first inning off Carlyle, before breaking through for four more runs in the second inning.
Two errors on one play by Yankees center fielder Austin Crum led to a Twins run, as Crum dropped a fly ball hit by Danny Valencia and Drew Butera followed with a sacrifice fly. Matt Tolbert, who was informed before the game that he'll make the Twins as a utility infielder, capped the four-run rally with a two-run triple. Carlyle was knocked out of the inning after recording just one out. In all, he allowed five runs (two earned) on three hits over 1 1/3 innings.
The Twins added another run in the third inning on an opposite-field home run by designated hitter Jim Thome off reliever Steve Garrison. Minnesota added another run in the fifth on a single by Butera that scored Rene Rivera.
The Yankees, though, scored three runs in the top of the fifth, keyed by an error by Tolbert at second base. Mark Teixeira plated two runs with a double, and Gustavo Molina brought home a run with a sacrifice fly.
Doug Bernier brought home another run for the Yankees in the sixth inning on a single that brought home Jesus Montero. It marked the last inning for Pavano, who allowed five runs on 11 hits over six innings in his last outing before Friday's scheduled Opening Day start against the Blue Jays.
"Pav was fine," Twins manager Ron Gardenhire said. "He just wanted 90 pitches. However it went or however many innings, he just wanted to get to 90 pitches, and that's exactly what he did."
Catcher Austin Romine was responsible for the Yankees' sixth run, homering off Chuck James in the eighth inning.
Up next for the Yankees: No. 2 starter A.J. Burnett makes his last Spring Training start when the Yankees host the Tampa Bay Rays at George M. Steinbrenner Field on Monday at 7:05 p.m. ET on MLB.TV. Burnett has a 2.77 ERA over four Grapefruit League starts, but perhaps more importantly, he has yet to walk a batter in 13 innings this spring.
Up next for the Twins: Minnesota will play its last game of the Grapefruit League season on Monday, hosting the Pirates at Hammond Stadium in a 12:05 p.m. CT start on MLB.TV. Left-hander Francisco Liriano is slated to start against Pirates righty Jeff Karstens. The Twins will head to Atlanta after the game to face the Braves in two exhibition games at Turner Field on Tuesday and Wednesday.