For Granderson, it was his first career start in the three-hole, though he has made three career appearances as the third-place hitter in the lineup.
"No difference at all, just be ready to hit," said Granderson, who has batted second all season. "You only bat third one time in the game. Any other time, the situation will dictate itself."
Granderson entered play Friday leading the Yankees and tying for second in the Majors with 26 home runs.