Manager Joe Girardi said that both pitchers were sore after their most recent outings in Tampa, Fla., and have been shut down indefinitely.
Feliciano has been bothered all season by a left rotator cuff strain, and Marte had surgery on his left shoulder last year. Girardi had said for some time that the Yankees couldn't count on either pitcher making it all the way back.
"I think knowing the severity of Feliciano's injury, I held out a little bit of hope, but I thought it would be really difficult for him to get back," Girardi said.
"I wasn't sure on Marte because he'd had the surgery and you didn't know. We knew the surgery was a serious surgery, and we didn't really know how he was going to respond to it."
Feliciano had been seen by Dr. James Andrews earlier this year and was attempting to rehabilitate his arm before undergoing surgery that could wipe out his entire 2012 season.
Thus, Feliciano may complete his two-year, $8 million deal with the Yankees without actually throwing a single regular-season pitch for them.
"If he has surgery, he's going to miss a whole year anyway, and it might be career-[ending]," Girardi said.