Granderson clubbed the milestone blast in the sixth inning of the Yankees' 4-2 victory over the Indians on Sunday at Progressive Field, taking reliever Tony Sipp deep over the right-field wall.
"It's cool to have accomplished it," Granderson said. "I didn't really know I was coming up on it until my aunt told me about it yesterday. It was neat to get it, and then I heard about the number of guys on our team that have done it, so the fact that we're all together on one team is pretty neat.
"It speaks a lot about what the organization is doing, and wants to do, by assembling that many guys on one team."
Granderson found a bucket of Moet & Chandon Champagne waiting on ice at his locker in acknowledgement of the feat, and his locker nameplate had been replaced by one reading "200."
The Yankees now have eight players with at least 200 career homers on their current roster, with Granderson joining Alex Rodriguez, Andruw Jones, Mark Teixeira, Raul Ibanez, Derek Jeter, Eric Chavez and Nick Swisher.
Still, Granderson considers himself a line-drive hitter who happens to hit the ball out of the park, and that doesn't figure to be changing any time soon.
"If I hit 500, maybe I might," Granderson said. "Yeah, that would put me in that [home run hitting] category."