"I guess it happens," Kuroda said through an interpreter. "I'll try to regroup myself and prepare for my next start."
Kuroda said that it was "tough to tell" if he'd be able to take his next turn in the rotation. He will throw a bullpen session on Friday in Detroit and should have a better idea then.
After Victorino's hit, Kuroda was seen on the mound by manager Joe Girardi and head athletic trainer Steve Donohue. He threw several warmup pitches to prove he could stay in the game, but Kuroda's command appeared to suffer as the inning continued.
"You're obviously concerned whenever it hits a pitcher's bare hand," Girardi said. "I saw him throw some warmup pitches after that and felt better about it, but obviously it started to bother him at the end because you saw him lose his command."
Kuroda hit Jackie Bradley Jr. with a pitch before inducing a Jose Iglesias fielder's choice for the first out of the inning. A walk to Jacoby Ellsbury followed, and Kuroda drilled Daniel Nava to force in Boston's second run of the evening.
"It looked good coming out of his hands, but then a couple pitches in the next at-bat, his ball just wasn't doing what you need it to do," catcher Chris Stewart said. "We knew it wasn't him. At that point he wasn't on. It was time to get him out of there."
Girardi removed Kuroda following his 41st pitch of the night. Kuroda was replaced by right-hander Cody Eppley, who was given as much time as needed to warm up because of the injury.
Eppley allowed four runs in 1 1/3 innings before Adam Warren saved the bullpen with 5 1/3 innings of one-run ball. Shawn Kelley finished up with a scoreless ninth inning.
Bryan Hoch is a reporter for MLB.com. Follow him on Twitter @bryanhoch and read his MLBlog, Bombers Beat. This story was not subject to the approval of Major League Baseball or its clubs.