The left-hander would have preferred to pitch in the series against the D-backs, as originally scheduled, but he said he understood the club's caution.
"I feel good; it was a good decision," Pettitte said. "I don't want to second-guess anybody. I'll go Friday. It's not that big of an issue. Hopefully, I'll feel great Friday."
Pettitte has looked terrific in his first two starts of the season, going 2-0 with a 1.20 ERA against the Red Sox and Indians, and he expressed some concern that the long layoff might affect his command in Toronto.
"I can tell I haven't pitched," Pettitte said. "I feel strong. I'm back to square one. When I get out there Friday, it's going to be trying to control yourself when you feel a little bit strong.
"Obviously, they want to see how I feel after this, and I'll be real excited if I come in [on Wednesday] and feel really, really good and have no tightness or anything like that creep up there after I worked it as hard as I did today. So we'll see what happens."
Bryan Hoch is a reporter for MLB.com. Follow him on Twitter @bryanhoch and read his MLBlog, Bombers Beat. This story was not subject to the approval of Major League Baseball or its clubs.