Ichiro's third-inning RBI single off the Indians' Scott Kazmir was the 2,654th hit of his big league career, tying Williams for 72nd place on the all-time hits list.
Williams assembled his total with the Red Sox from 1939-60, losing three years of his career to military service during World War II. Ichiro's total is also lower than it theoretically could have been; while playing in Japan, he amassed 1,278 hits that are not counted toward his Major League total.
The next names on the all-time hits list are George Davis and Harry Heilmann, who are tied for 70th with 2,660 big league hits apiece.
Josh Vitale is an associate reporter for MLB.com. Bryan Hoch is a reporter for MLB.com. Follow him on Twitter @bryanhoch and read his MLBlog, Bombers Beat. This story was not subject to the approval of Major League Baseball or its clubs.